Fox V L, Abel S D, Malas S, Duggan C, Leichtner A M
Combined Program in Pediatric Gastroenterology and Nutrition, Children's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.
Gastrointest Endosc. 1997 Jan;45(1):64-71. doi: 10.1016/s0016-5107(97)70304-3.
Percutaneous endoscopic gastrostomy has gained wide acceptance for patients who require prolonged tube feeding support. We sought to identify complications and associated risk factors of endoscopic gastrostomy and subsequent catheter replacement in pediatric patients.
Medical records were reviewed for 137 patients. Odds ratios were calculated for complications related to patient age, weight, weight-for-age Z score, and principal diagnosis.
Seventeen patients (12.4%) developed significant complications after gastrostomy: cellulitis occurred in 10 patients (7.3%); other complications included gastrocolic fistula (2), duodenal hematoma (1), complicated pneumoperitoneum (1), necrotizing fasciitis (1), gastric perforation (1), and catheter migration (1). Patients with cancer had significantly greater odds for developing a wound infection, and patients with AIDS had significantly greater odds for total complications. A trend toward increased wound infection was observed in patients with cardiac disease. Age, weight, and weight-for-age Z score were not associated with adverse outcome. Two complications occurred in 85 patients (2.4%) after gastrostomy catheter replacement.
Pediatric patients with cancer and AIDS are at increased risk for complications after endoscopic gastrostomy regardless of age, weight, or nutritional status. Infrequent yet life-threatening complications may occur after replacement of initial gastrostomy catheter.
经皮内镜下胃造口术已被广泛应用于需要长期管饲支持的患者。我们试图确定儿科患者内镜下胃造口术及后续导管更换的并发症及相关危险因素。
回顾了137例患者的病历。计算了与患者年龄、体重、年龄别体重Z评分和主要诊断相关的并发症的比值比。
17例患者(12.4%)在胃造口术后出现严重并发症:10例患者(7.3%)发生蜂窝织炎;其他并发症包括胃结肠瘘(2例)、十二指肠血肿(1例)、复杂性气腹(1例)、坏死性筋膜炎(1例)、胃穿孔(1例)和导管移位(1例)。癌症患者发生伤口感染的几率显著更高,艾滋病患者发生总体并发症的几率显著更高。观察到心脏病患者伤口感染有增加的趋势。年龄、体重和年龄别体重Z评分与不良结局无关。85例患者(2.4%)在胃造口术导管更换后出现2例并发症。
无论年龄、体重或营养状况如何,患有癌症和艾滋病的儿科患者内镜下胃造口术后发生并发症的风险增加。更换初始胃造口术导管后可能会出现罕见但危及生命的并发症。