Understanding the chiral pharmacology of nonsteroidal antiinflammatory drugs in the aryl propionic acid class: S(+) ibuprofen. Overview of the symposium "update on S(+) ibuprofen" (Going/Kitzbuehl, Austria, February 2-4, 1996). - Suppr | 超能文献

Understanding the chiral pharmacology of nonsteroidal antiinflammatory drugs in the aryl propionic acid class: S(+) ibuprofen. Overview of the symposium "update on S(+) ibuprofen" (Going/Kitzbuehl, Austria, February 2-4, 1996).

作者信息

Wechter W J

出版信息

J Clin Pharmacol. 1996 Dec;36(12 Suppl):1S-2S.

Abstract

摘要

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

文档翻译

学术文献翻译模型，支持多种主流文档格式。

相似文献

1

Understanding the chiral pharmacology of nonsteroidal antiinflammatory drugs in the aryl propionic acid class: S(+) ibuprofen. Overview of the symposium "update on S(+) ibuprofen" (Going/Kitzbuehl, Austria, February 2-4, 1996).

J Clin Pharmacol. 1996 Dec;36(12 Suppl):1S-2S.

2

Nonsteroidal antiinflammatory drug modulation of behavioral responses to intrathecal N-methyl-D-aspartate, but not to substance P and amino-methyl-isoxazole-propionic acid in the rat.非甾体抗炎药对大鼠鞘内注射N-甲基-D-天冬氨酸所引起行为反应的调节作用，但对P物质和氨基甲基异恶唑丙酸所引起的行为反应无调节作用。

J Clin Pharmacol. 1996 Dec;36(12 Suppl):20S-26S.

3

Pharmacodynamics and pharmacokinetics of the profens: enantioselectivity, clinical implications, and special reference to S(+)-ibuprofen.丙酸类药物的药效学和药代动力学：对映体选择性、临床意义及对S(+)-布洛芬的特别参考

J Clin Pharmacol. 1996 Dec;36(12 Suppl):7S-15S.

4

Inhibition of cyclooxygenase-1 and -2 by R(-)- and S(+)-ibuprofen.R(-)-和S(+)-布洛芬对环氧合酶-1和-2的抑制作用。

J Clin Pharmacol. 1996 Dec;36(12 Suppl):16S-19S.

5

Protein profile in neuroblastoma cells incubated with S- and R-enantiomers of ibuprofen by iTRAQ-coupled 2-D LC-MS/MS analysis: possible action of induced proteins on Alzheimer's disease.通过iTRAQ耦合二维液相色谱-串联质谱分析，研究布洛芬S-和R-对映体孵育的神经母细胞瘤细胞中的蛋白质谱：诱导蛋白对阿尔茨海默病的可能作用。

Proteomics. 2008 Apr;8(8):1595-607. doi: 10.1002/pmic.200700556.

6

Resolution of enantiomers of ibuprofen by liquid chromatography: a review.液相色谱法拆分布洛芬对映体：综述

Biomed Chromatogr. 1998 Nov-Dec;12(6):309-16. doi: 10.1002/(SICI)1099-0801(199811/12)12:6<309::AID-BMC763>3.0.CO;2-K.

7

Superior effectiveness of ibuprofen compared with other NSAIDs for reducing the survival of human prostate cancer cells.与其他非甾体抗炎药相比，布洛芬在降低人前列腺癌细胞存活率方面具有更高的有效性。

Cancer Chemother Pharmacol. 2002 Oct;50(4):277-84. doi: 10.1007/s00280-002-0485-8. Epub 2002 Aug 27.

8

The aryl propionic acid R-flurbiprofen selectively induces p75NTR-dependent decreased survival of prostate tumor cells.芳基丙酸R-氟比洛芬选择性诱导p75神经营养因子受体依赖的前列腺肿瘤细胞存活率降低。

Cancer Res. 2007 Apr 1;67(7):3254-62. doi: 10.1158/0008-5472.CAN-06-3657.

9

Modulation of transcription factor NF-kappaB by enantiomers of the nonsteroidal drug ibuprofen.非甾体类药物布洛芬对映体对转录因子NF-κB的调节作用

Br J Pharmacol. 1998 Feb;123(4):645-52. doi: 10.1038/sj.bjp.0701652.

10

R- and S-isomers of nonsteroidal anti-inflammatory drugs differentially regulate cytokine production.非甾体抗炎药的R型和S型异构体对细胞因子的产生有不同的调节作用。

Eur Cytokine Netw. 2000 Jun;11(2):185-92.

引用本文的文献

1

S(+)-ibuprofen (dexibuprofen)--Excellent tolerance has not to be combined with poor clinical efficacy.S(+)-布洛芬（右旋布洛芬）——极好的耐受性并不需要与较差的临床疗效相结合。

Inflammopharmacology. 1998;6(1):75-9. doi: 10.1007/s10787-998-0008-2.

2

Clinical pharmacokinetics of ibuprofen. The first 30 years.布洛芬的临床药代动力学。头30年

Clin Pharmacokinet. 1998 Feb;34(2):101-54. doi: 10.2165/00003088-199834020-00002.