Okabayashi T, Tsutiya K, Muramatsu Y, Ueno H, Morita C
Department of Veterinary Public Health, Rakuno Gakuen University, Hokkaido, Japan.
Microbiol Immunol. 1996;40(12):895-8. doi: 10.1111/j.1348-0421.1996.tb01157.x.
In Thailand, the first human cases of spotted fever group rickettsiosis were reported in 1994, but no serosurveys on wild rats have yet been conducted. We investigated the seroepidemiology in wild rats collected in the 1970s from two regions in Thailand, and found a 62.2% positive rate of antibodies for spotted fever group rickettsia (SFGR) by the indirect immunofluorescence antibody test. Of the antibody-positive rats, 82.2% had higher titers of antibodies against TT-118 than those against Rickettsia japonica, which suggests that Thailand is infested mainly with the TT-118 strain or its antigenically related organisms. The prevalence of antibodies in Bandicota indica was significantly higher than that in other species, which suggests that B. indica is important as a reservoir of SFGR in Thailand.
1994年泰国报告了首例人感染斑点热群立克次体病病例，但尚未对野生大鼠进行血清学调查。我们调查了20世纪70年代从泰国两个地区采集的野生大鼠的血清流行病学，通过间接免疫荧光抗体试验发现斑点热群立克次体（SFGR）抗体阳性率为62.2%。在抗体阳性的大鼠中，82.2%针对TT-118的抗体效价比针对日本立克次体的抗体效价更高，这表明泰国主要感染的是TT-118菌株或其抗原相关的微生物。板齿鼠的抗体流行率显著高于其他物种，这表明板齿鼠作为泰国SFGR的储存宿主很重要。
