Kondo T
Department of Neurology, Juntendo University School of Medicine.
Nihon Rinsho. 1997 Jan;55(1):118-22.
Reports on cases of parkinsonism associated with brain tumor were reviewed. Although parkinsonism can develop in association with any type of brain tumor, it develops most frequently in association with meningiomas located at the sphenoid ridge or frontal convexity. Although parkinsonian symptoms in the parkinsonism associated with brain tumors are similar to those seen in Parkinson's disease in the early stages, atypical symptoms, such as visual field defects, motor weakness or pyramidal signs are visible signs of the parkinsonism. Functional abnormality in the nigrostrial system due to chronic mechanical compression of the system by a sizeable brain tumor seems to contribute to the pathogenesis of the parkinsonism.
对与脑肿瘤相关的帕金森综合征病例报告进行了综述。虽然帕金森综合征可与任何类型的脑肿瘤相关联而发生,但最常与位于蝶骨嵴或额叶凸面的脑膜瘤相关。虽然与脑肿瘤相关的帕金森综合征的帕金森症状在早期与帕金森病所见症状相似,但非典型症状,如视野缺损、运动无力或锥体束征,是该帕金森综合征的明显体征。由于相当大的脑肿瘤对黑质纹状体系统的慢性机械压迫导致该系统功能异常,似乎是该帕金森综合征发病机制的一个因素。