Klufio G O, Bentsi I K, Yeboah E D, Quartey J K
Department of Surgery, University of Ghana Medical School, Accra, Ghana.
West Afr J Med. 1996 Jul-Sep;15(3):173-6.
Fifty-one patients with newly diagnosed upper urinary tract stones were seen at the Korle Bu Teaching Hospital, Accra over an 8 years period from September 1985 to August 1993. Their mean age was 40.1 years (range 20-61 years). The sex ratio was 36 males to 15 males. During the same period 3, 217, 135 patients (both adults and children) attended the hospital's clinics. Thus putting the incidence of upper urinary tract stone at 2 per 100,000. On presentation 37 patients had solitary stones, 11 had multiple stone and 3 had partial or complete staghorn calculi. A total of 71 stones were seen; 30 were renal and 35 ureteric. The etiology of the stone disease was established in only 10 cases (20%). Urinary stasis was a predisposing factors in 5 patients, urinary infection in 3 others and hyperuricaemia and uricosuria in another 2. Stones from 29 patients that were removed at surgery or passed spontaneously were analysed chemically. Of these 25 (86%) consisted of calcium oxalate and/or calcium phosphate, 3 (10%) consisted of magnesium ammonium phosphate and 1(4%) contained only uric acid.
1985年9月至1993年8月的8年期间,在阿克拉的科勒布教学医院共诊治了51例新诊断的上尿路结石患者。他们的平均年龄为40.1岁(范围20 - 61岁)。男女比例为36例男性对15例女性。在同一时期,共有3,217,135名患者(包括成人和儿童)到该医院门诊就诊。因此,上尿路结石的发病率为每10万人中有2例。就诊时,37例患者为单发结石,11例为多发结石,3例为部分或完全鹿角形结石。总共发现了71颗结石;其中30颗位于肾脏,35颗位于输尿管。仅在10例(20%)中确定了结石病的病因。尿路梗阻是5例患者的诱发因素,尿路感染是另外3例的诱发因素,高尿酸血症和尿酸尿症是另外2例的诱发因素。对29例经手术取出或自行排出的结石进行了化学分析。其中25例(86%)由草酸钙和/或磷酸钙组成,3例(10%)由磷酸镁铵组成,1例(4%)仅含尿酸。