Matthes J W, Lewis P A, Davies D P, Bethel J A
Department of Child Health, Singleton Hospital, Swansea, West Glamorgan.
Arch Dis Child. 1996 Dec;75(6):521-3. doi: 10.1136/adc.75.6.521.
Factors that influence low birth weight at term may also be associated with subcutaneous fat patterning in later life. This hypothesis was investigated in a comparative (retrospective) cohort study. The subjects, born in Cardiff between 1975 and 1977, were of mean age 15.7 years. Cases (low birth weight (< 2500 g) at term) were matched with controls (normal birth weight (3000-3800 g) at term) for sex, parity, place of birth, date of birth, and gestation. Subscapular skinfold (an index of central subcutaneous fat) and triceps skinfold (an index of peripheral subcutaneous fat) were measured using a Holtain skinfold caliper. The differences (cases minus controls) (95% confidence interval) for subscapular and triceps skinfolds were respectively -0.3 mm (-1.74 to 1.14) and -0.48 mm (-1.75 to 0.79). These findings are inconsistent with the hypothesis that low birth weight at term is associated with subcutaneous fat patterning in adolescence.
足月低出生体重的影响因素可能也与日后皮下脂肪分布有关。这一假说在一项比较性(回顾性)队列研究中进行了调查。研究对象于1975年至1977年在加的夫出生,平均年龄为15.7岁。病例组(足月低出生体重(<2500克))与对照组(足月正常出生体重(3000 - 3800克))在性别、胎次、出生地、出生日期和孕周方面进行了匹配。使用霍尔坦皮褶厚度仪测量肩胛下皮褶(中央皮下脂肪指标)和肱三头肌皮褶(外周皮下脂肪指标)。肩胛下皮褶和肱三头肌皮褶的差异(病例组减去对照组)(95%置信区间)分别为-0.3毫米(-1.74至1.14)和-0.48毫米(-1.75至0.79)。这些发现与足月低出生体重与青春期皮下脂肪分布有关这一假说不一致。