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用于动脉导管封堵的栓塞线圈的应用进展。

Evolving use of embolisation coils for occlusion of the arterial duct.

作者信息

Rosenthal E, Qureshi S A, Reidy J, Baker E J, Tynan M

机构信息

Department of Paediatric Cardiology, Guy's Hospital, London.

出版信息

Heart. 1996 Dec;76(6):525-30. doi: 10.1136/hrt.76.6.525.

Abstract

OBJECTIVE

To assess the outcome of arterial duct occlusion with coils chosen according to the duct morphology.

DESIGN

Retrospective study.

SETTING

Paediatric cardiology centre.

PATIENTS

Coil occlusion was attempted in 57 patients aged 0.5 to 15 (median 3.7) years and weighing 5-59 (median 14) kg between January 1991 and December 1995. A residual leak was present in 8 patients after umbrella closure and in 4 patients after duct ligation.

METHODS

Coils of 4 different types were implanted through 4 or 5 F femoral artery catheters. Platinum or Interlocking Detachable 0.018 inch coils were deployed completely inside tubular ducts. Gianturco or PDA controlled release 0.038 inch coils were implanted to straddle short, post ligation and post umbrella ducts.

RESULTS

Coil implantation was successful in 54/57 patients. At 1 year the cumulative occlusion rate was 53/57 ducts (93%) on an intention to treat analysis. A single coil was implanted in 37 (69%), 2 coils in 10 (19%), 3 coils in 3 (5%) and 4 coils in 4 (7%) of the 54 successful procedures. Duct occlusion was documented at the end of the procedure in 31%, by the following day in 83%, by 6 weeks in 87%, by 6 months in 96%, and by 1 year in 98%. Coil embolisation occurred in 6/58 procedures (10%), with a 50% rate in the first year of implantation (1/2 patients) falling to 7% in the last year (3/42 patients). All embolised coils were easily retrieved.

CONCLUSIONS

Occlusion of small to moderate size arterial ducts, including residual post umbrella or post ligation ducts, was readily accomplished by coils selected according to the duct anatomy. This has both cost and practical benefits.

摘要

目的

评估根据动脉导管形态选择弹簧圈进行动脉导管封堵的效果。

设计

回顾性研究。

地点

儿科心脏病中心。

患者

1991年1月至1995年12月期间,对57例年龄0.5至15岁(中位数3.7岁)、体重5至59千克(中位数14千克)的患者尝试进行弹簧圈封堵。8例患者在使用封堵伞封堵后仍有残余分流,4例患者在动脉导管结扎术后仍有残余分流。

方法

通过4或5F股动脉导管植入4种不同类型的弹簧圈。铂或互锁可拆式0.018英寸弹簧圈完全部署在管状导管内。Gianturco或PDA控释0.038英寸弹簧圈植入以跨越短的、结扎后和封堵伞后的导管。

结果

54/57例患者弹簧圈植入成功。在意向性治疗分析中,1年时累计封堵率为53/57条导管(93%)。在54例成功手术中,37例(69%)植入单个弹簧圈,10例(19%)植入2个弹簧圈,3例(5%)植入3个弹簧圈,4例(7%)植入4个弹簧圈。手术结束时31%的导管被记录封堵,术后第2天83%,6周时87%,6个月时96%,1年时98%。58例手术中有6例(10%)发生弹簧圈栓塞,植入后第一年发生率为50%(2例中的1例),最后一年降至7%(42例中的3例)。所有栓塞的弹簧圈均易于取出。

结论

根据导管解剖结构选择弹簧圈,可轻松实现中小尺寸动脉导管的封堵,包括封堵伞后或结扎后的残余导管。这具有成本效益和实际益处。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/43e2/484607/c9f59334131b/heart00028-0091-a.jpg

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