原发性甲状旁腺功能亢进症中纤维囊性骨炎的自发愈合

Gibbs C J, Millar J G, Smith J

Department of Endocrine Medicine, Southampton University, Portsmouth, UK.

Postgrad Med J. 1996 Dec;72(854):754-7. doi: 10.1136/pgmj.72.854.754.

A 24-year-old man with primary hyperparathyroidism and osteitis fibrosa cystica developed acute hypocalcaemia. Spontaneous healing of his bone disease was confirmed radiographically and by correction of the serum alkaline phosphatase. Hypercalcaemia associated with a raised serum parathyroid hormone recurred 90 weeks after the initial presentation. During the fourth neck exploration a parathyroid adenoma was removed, resulting in resolution of his condition. Haemorrhagic infarction of an adenoma was the most likely cause of the acute hypocalcaemic episode.

一名患有原发性甲状旁腺功能亢进症和纤维囊性骨炎的24岁男性发生了急性低钙血症。通过X线检查及血清碱性磷酸酶的恢复证实了其骨病的自然愈合。在初次就诊90周后，再次出现与血清甲状旁腺激素升高相关的高钙血症。在第四次颈部探查时切除了甲状旁腺腺瘤，其病情得以缓解。腺瘤的出血性梗死很可能是急性低钙血症发作的原因。