Swenson L, Audell L, Hedhammar A
Department of Animal Breeding, Faculty of Agriculture, Swedish University of Agricultural Sciences, Uppsala, Sweden.
J Am Vet Med Assoc. 1997 Jan 15;210(2):215-21.
To determine the prevalence and charges over time in the prevalence of elbow arthrosis in Bernese Mountain Dogs and Rottweilers, to ascertain whether prevalence or severity of elbow arthrosis was associated with sex of the dogs, age at the time of elbow joint examination, or ancestral background, to determine the effects of selective breeding, and to conduct an economic evaluation of the elbow arthrosis program operated by the Swedish Kennel Club.
Analysis of radiographic evaluations of elbow joint conformity.
4,515 dogs from 2 breeds registered by the Swedish Kennel Club.
All radiographs were scrutinized by a single radiologist (LA), and elbow joint conformation was classified as normal or arthrotic, with the degree of arthrosis classified as 1, 2, or 3.
Decreasing prevalence of elbow arthrosis corresponding to selection of breeding stock and high heritabilities was found. Sex differences were documented in both breeds, but with contradictory directions. This was interpreted as breed differences in the distribution of genes related to elbow arthrosis. Economic analyses showed that costs of screening and registration of elbow joints was less than the value of dogs estimated to have been saved from moderate and severe elbow arthrosis in both breeds.
Documented effects of age suggest that all dogs should be screened at the same age, rather than screening a few dogs at an older, more revealing age. In screening and control programs based on an open registry with access to family records, decreasing prevalence of elbow arthrosis can be expected, and related to selection of breeding stock.
确定伯恩山犬和罗威纳犬肘关节病的患病率及随时间的变化情况，确定肘关节病的患病率或严重程度是否与犬的性别、肘关节检查时的年龄或祖先背景有关，确定选择性育种的影响，并对瑞典养犬俱乐部实施的肘关节病项目进行经济评估。
对肘关节符合度的X线评估进行分析。
瑞典养犬俱乐部登记的2个品种的4515只犬。
所有X线片由一名放射科医生（LA）仔细检查，肘关节形态分为正常或关节病，关节病程度分为1、2或3级。
发现随着种畜选择和高遗传力，肘关节病患病率降低。两个品种均记录到性别差异，但方向相反。这被解释为与肘关节病相关基因分布的品种差异。经济分析表明，两个品种肘关节筛查和登记的成本低于预计因中度和重度肘关节病而挽救的犬的价值。
年龄的记录效应表明，所有犬都应在相同年龄进行筛查，而不是在年龄较大、更能揭示问题的阶段对少数犬进行筛查。在基于开放登记处且可获取家族记录的筛查和控制项目中，肘关节病的患病率有望降低，且与种畜选择有关。
