Mäki K, Liinamo A E, Ojala M
Department of Animal Science, Helsinki University, Finland.
J Anim Sci. 2000 May;78(5):1141-8. doi: 10.2527/2000.7851141x.
Data from 2,764 Rottweiler dogs born from 1987 to 1996 were analyzed with a Restricted Maximum Likelihood procedure using a mixed linear animal model to obtain variance component estimates for hip and elbow dysplasia. The data included 2,764 hip dysplasia and 2,278 elbow dysplasia records. Hip joints were scored as normal (0), borderline (1), slight (2), moderate (3), and severe (4, 4.5, and 5) hip dysplasia. Elbow joints were graded normal or borderline (0), slight (1), moderate (2), and severe (3) elbow dysplasia. The mean for the hip scores was 1.07 and for the elbow scores .60. Environmental effects influencing hip dysplasia were age, birth year, birth year x season interaction, and experience of the veterinarian responsible for x-raying the dog. For elbow dysplasia, statistically significant effects were age, birth year, sex of the dog, and panelist responsible for each screening. Estimates of heritability for hip and elbow dysplasia were .58 +/- .04 and .31 +/- .04, respectively, with a genetic correlation of .37 +/- .08 between the traits. Genetic improvement of almost one genetic standard deviation was observed in both traits during the 10 yr covered by the data.
对1987年至1996年出生的2764只罗威纳犬的数据进行分析，采用限制最大似然法，使用混合线性动物模型来获得髋关节和肘关节发育不良的方差成分估计值。数据包括2764条髋关节发育不良记录和2278条肘关节发育不良记录。髋关节评分分为正常（0）、临界（1）、轻度（2）、中度（3）和重度（4、4.5和5）髋关节发育不良。肘关节分级为正常或临界（0）、轻度（1）、中度（2）和重度（3）肘关节发育不良。髋关节评分的平均值为1.07，肘关节评分的平均值为0.60。影响髋关节发育不良的环境因素有年龄、出生年份、出生年份×季节交互作用以及负责给狗进行X光检查的兽医的经验。对于肘关节发育不良，具有统计学意义的影响因素有年龄、出生年份、狗的性别以及负责每次筛查的评审员。髋关节和肘关节发育不良的遗传力估计值分别为0.58±0.04和0.31±0.04，这两个性状之间的遗传相关性为0.37±0.08。在数据涵盖的10年期间，这两个性状均观察到近一个遗传标准差的遗传进展。
