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[慢性淋巴细胞性胃炎的病因发病机制与治疗的相关性]

[The etiopathogenetic and therapeutic correlations in chronic lymphocytic gastritis].

作者信息

Mateş I N, Constantinoiu S M, Pop D, Diculescu M

机构信息

Spitalul Clinic Griviţa, Bucureşti.

出版信息

Chirurgia (Bucur). 1996 May-Jun;45(3):139-45.

PMID:9019268
Abstract

Haot et. al. (1,2) described in 1985 a new histopathologic entity, the lymphocytic gastritis, characterised by large number of intraepithelial T cells. The condition is usually symptomatic and related to an endoscopic form of gastropathy; it has an easily recognizable histology. According to The Sydney System it is classified as a special form (3); no etiopathogenic relation is established. The clinical significance and treatment are currently unclear (4). In one case, affected by peripheric T cell disfunction, there was significant clinical, endoscopic and histologic improvement after vagotomy, hemigastrectomy and total duodenal diversion. The possible favorable effect of surgery on lymphocytic gastritis, a diffuse gastric pathology, is discussed. To our knowledge this has not been reported before.

摘要

豪特等人(1,2)于1985年描述了一种新的组织病理学实体——淋巴细胞性胃炎,其特征是上皮内有大量T细胞。这种情况通常有症状,且与一种内镜下的胃病形式有关;它有易于识别的组织学表现。根据悉尼系统,它被归类为一种特殊形式(3);尚未确立病因关系。目前其临床意义和治疗尚不清楚(4)。在一例受外周T细胞功能障碍影响的病例中,迷走神经切断术、半胃切除术和十二指肠全转流术后,临床、内镜和组织学方面都有显著改善。本文讨论了手术对淋巴细胞性胃炎(一种弥漫性胃部病变)可能产生的有利影响。据我们所知,此前尚未有过相关报道。

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