Balzer S, Küttner K
Klinik für Hals-Nasen-Ohren-Krankheiten und plastische Chirurgie, Klinikum Suhl.
HNO. 1996 Oct;44(10):559-66. doi: 10.1007/s001060050054.
The brainstem auditory evoked responses (BAERs) of 87 patients with chronic renal failure (average age 51 years) were examined according to serum creatinine levels, the nature of the chronic renal disease present and the effect of dialysis. Changes recorded were followed over a period of 3 years. Altogether BAERs of 272 ears were evaluated. Results demonstrated changes in wave morphology and abnormal prolongations of all wave latencies and interpeak intervals. Wave V latencies and the interpeak interval for waves I-V showed a correlation to serum creatinine levels. The direct positive effect of dialysis was reflected in shortening of all wave latencies. The nature of the chronic renal disease and the existence of coexistence diseases were not important for changes in central BAER responses. The recording of the intra-individual course of a BAER permitted documentation of worsened cerebral function even in patients with constant uremic conditions.
根据血清肌酐水平、慢性肾病的类型以及透析效果，对87例慢性肾衰竭患者（平均年龄51岁）的脑干听觉诱发电位（BAER）进行了检测。在3年的时间里对记录的变化情况进行了跟踪。共评估了272只耳朵的BAER。结果显示波形形态发生改变，所有波潜伏期和峰间期均异常延长。波V潜伏期以及波I-V的峰间期与血清肌酐水平相关。透析的直接积极作用表现为所有波潜伏期缩短。慢性肾病的类型和并存疾病的存在对中枢BAER反应的变化并不重要。对BAER个体病程的记录能够证明，即使在尿毒症病情稳定的患者中，脑功能也会恶化。
