Gafter U, Shvili Y, Levi J, Talmi Y, Zohar Y
Department of Nephrology, Hasharon Hospital, Tel Aviv University Medical School, Petah-Tiqva, Israel.
Nephron. 1989;53(1):2-5. doi: 10.1159/000185692.
Brainstem auditory evoked responses (BAER) were recorded in patients with chronic renal failure before commencement of chronic dialysis treatment, and in patients with end-stage renal failure on chronic hemodialysis for several years. Both groups of patients had delayed latencies of the third and fifth waves. The patients on hemodialysis revealed delayed latency of interpeak I-V as well. There was no correlation between wave latency, serum urea, creatinine, PTH or duration of chronic hemodialysis treatment. A hemodialysis session led to a slight shortening of the third wave. This study suggests that neural conduction along the brainstem in patients with chronic renal failure is delayed even before hemodialysis is started. Although 1 dialysis session may have some beneficial effect, long-term hemodialysis treatment does not seem to shorten the delay in neural conduction observed in patients with chronic renal failure.
在慢性透析治疗开始前，对慢性肾衰竭患者进行了脑干听觉诱发电位（BAER）记录，并对接受慢性血液透析数年的终末期肾衰竭患者进行了记录。两组患者的第三波和第五波潜伏期均延迟。接受血液透析的患者还表现出峰间I-V潜伏期延迟。波潜伏期、血清尿素、肌酐、甲状旁腺激素或慢性血液透析治疗持续时间之间无相关性。一次血液透析会导致第三波稍有缩短。本研究表明，慢性肾衰竭患者即使在开始血液透析之前，沿脑干的神经传导就已延迟。尽管一次透析可能有一些有益作用，但长期血液透析治疗似乎并未缩短慢性肾衰竭患者观察到的神经传导延迟。
