Coggle J E
Br J Radiol. 1977 Sep;50(597):658-62. doi: 10.1259/0007-1285-50-597-658.
The long-term effects of partial body exposure of one-day-old mice given either 60Co gamma rays or negative pions have been studied. Both radiations produced considerable life-shortening; for pions 6.8 +/- 1.5% of life is lost per 100 rad and for gamma rays the value is 5.7 +/- 0.5% per 100 rad. The RBE of pions for ten weeks of life-shortening is about 1.3 compared with 60Co gamma rays, although at lower doses the RBE may be higher reaching about two for six weeks of life shortening. The incidence rate of tumours at any particular age was greater in mice irradiated with pions at the peak and in those given higher doses of gamma rays than in the controls.
研究了给一日龄小鼠局部身体照射60Coγ射线或负π介子的长期影响。两种辐射都导致了显著的寿命缩短；对于π介子，每100拉德损失6.8±1.5%的寿命，对于γ射线，每100拉德的值为5.7±0.5%。与60Coγ射线相比，π介子导致寿命缩短十周的相对生物效应约为1.3，尽管在较低剂量下，相对生物效应可能更高，在导致寿命缩短六周时约为2。在任何特定年龄，处于峰值的π介子照射小鼠和接受较高剂量γ射线照射的小鼠的肿瘤发生率均高于对照组。
