Khan A, Jilani F, Kaye S, Greenberg B R
Division of Hematology/Oncology, University of Connecticut Health Center, Farmington 06030, USA.
Am J Clin Oncol. 1997 Feb;20(1):73-7. doi: 10.1097/00000421-199702000-00016.
Primary malignant tumors of the aorta are rare, only a handful of isolated cases having been described in the literature. Preoperative diagnosis of these tumors is more the exception than the rule. Diagnosis of aortic tumors is difficult as they can mimic many diverse conditions including atherosclerosis. We report a patient who presented with lower extremity claudication, renal infarction, and diffuse atherosclerosis and who was found to have tumor fragments in blood clots but no evidence of a primary tumor. Immunohistochemistry narrowed the differential diagnosis to a type of sarcoma. Six months later, he developed right flank pain due to a malignant fibrous histiocytoma that involved the abdominal aorta and that had initially manifested as tumor emboli.
主动脉原发性恶性肿瘤很罕见，文献中仅描述过少数孤立病例。这些肿瘤的术前诊断更多是例外而非常规。主动脉肿瘤的诊断很困难，因为它们可模仿多种不同病症，包括动脉粥样硬化。我们报告一名患者，其表现为下肢间歇性跛行、肾梗死和弥漫性动脉粥样硬化，在血凝块中发现有肿瘤碎片，但无原发性肿瘤证据。免疫组织化学将鉴别诊断范围缩小至一种肉瘤。六个月后，他因恶性纤维组织细胞瘤出现右侧胁腹疼痛，该肿瘤累及腹主动脉，最初表现为肿瘤栓子。
