Staffurth J S, Gibberd M C, Fui S N
Br Med J. 1977 Sep 10;2(6088):688-90. doi: 10.1136/bmj.2.6088.688.
In 262 patients with thyrotoxicosis and atrial fibrillation there were 26 episodes of arterial embolism (17 cerebral and nine elsewhere) in 21 patients. Twelve incidents occurred with active thyrotoxicosis, three on reversion to sinus rhythm, and 11 after the patients were euthyroid. This important complication is more common than is realised, and most patients should be put on prophylactic anticoagulants when first seen with atrial fibrillation.
在262例甲状腺毒症合并心房颤动的患者中,21例患者发生了26次动脉栓塞事件(17次脑部栓塞,9次其他部位栓塞)。12次事件发生在甲状腺毒症活动期,3次发生在恢复窦性心律时,11次发生在患者甲状腺功能正常后。这种重要的并发症比人们意识到的更为常见,大多数患者首次出现心房颤动时就应接受预防性抗凝治疗。