Eppley B L, Sadove A M
Craniofacial Program, Indiana University Medical Center, Indianapolis, IN 46202-5200, USA.
J Craniofac Surg. 1995 Nov;6(6):477-82. doi: 10.1097/00001665-199511000-00011.
The use of resorbable bone fixation devices composed of a copolymer of polyglycolic acid and polylactic acid were investigated in an animal model as well as in human application. We used resorbable plates and metallic microscrews in immature rabbits; plating of the coronal suture resulted in complete device resorption and increased interscrew distances (i.e., growth across the suture) after 8 postoperative months. In 20 infants with calvarial deformities, thin, straight resorbable plates were used for skeletal fixation after osteotomies and repositioning. A total of 231 fixation devices were implanted without complications after 12 postoperative months. These encouraging results have led to further clinical application in craniosynostosis deformities.
在动物模型以及人体应用中，对由聚乙醇酸和聚乳酸共聚物组成的可吸收骨固定装置的使用进行了研究。我们在未成熟的兔子身上使用了可吸收板和金属微螺钉；冠状缝植板术后8个月，装置完全吸收，螺钉间距增加（即缝线处生长）。在20例患有颅骨畸形的婴儿中，截骨和重新定位后使用薄而直的可吸收板进行骨骼固定。术后12个月共植入231个固定装置，无并发症。这些令人鼓舞的结果促使其在颅缝早闭畸形中得到进一步的临床应用。
