Santoshkumar B, Radhakrishnan K
Department of Neurology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, India.
Electroencephalogr Clin Neurophysiol. 1996 Nov;99(5):440-3. doi: 10.1016/s0013-4694(96)96540-2.
We report a 15 year old girl with a childhood hemiplegia, who developed a recent progressive intellectual decline associated with elevated globulins and measles antibody titres in the cerebrospinal fluid, indicating a diagnosis of subacute sclerosing panencephalitis (SSPE). The magnetic resonance imaging revealed left hemispheric atrophy concordant with a long-standing right hemiplegia, and electroencephalography exhibited lateralized periodic complexes (PCs) over the right hemisphere concordant with left-sided myoclonic jerks. The modification of PCs in our patient due to preexisting damaged cerebral hemisphere illustrate that a fairly functional cortex and subcortical white matter are needed for the expression of the PCs of SSPE.
