Akiyama Y, Kondo H, Shirono R, Fujii Y
Dept. of Respiratory Medicine, Komatsushima Red Cross Hospital.
Gan To Kagaku Ryoho. 1997 Jan;24(1):93-6.
A 69-year-old male was admitted to our hospital because of dry cough. Chest X-P and CT scans showed a mass shadow in the right lung, thickening of pulmonary vessels and pleural effusion. Cytological examination of transbronchial brushing specimen revealed lung adenocarcinoma. Cancer cells were also detected in pleural effusion. High levels of CA 19.9 were noticed: 48,400 U/ml in serum and 395,000 U/ml in pleural effusion, respectively. Two courses of combined chemotherapy (CDDP + VDS) were done. Concurrent chest radiation therapy (40 Gy) to primary tumor was also performed. After treatment the primary tumor decreased in size on CT scan analysis, but the patient suffered from respiratory failure due to the increase of sputa and pleural effusion and died 104 days after admission.
一名69岁男性因干咳入院。胸部X线片和CT扫描显示右肺有肿块阴影、肺血管增厚和胸腔积液。经支气管刷检标本的细胞学检查显示为肺腺癌。胸腔积液中也检测到癌细胞。发现CA 19.9水平升高：血清中为48400 U/ml，胸腔积液中为395000 U/ml。进行了两个疗程的联合化疗（顺铂+长春地辛）。同时对原发肿瘤进行了胸部放射治疗（40 Gy）。治疗后，CT扫描分析显示原发肿瘤体积缩小，但患者因痰液增多和胸腔积液增加而出现呼吸衰竭，入院104天后死亡。
