LALNVIEW：一种用于成对序列比对的图形化查看器。

LALNVIEW: a graphical viewer for pairwise sequence alignments.

作者信息

Duret L, Gasteiger E, Perrière G

机构信息

Department of Medical Biochemistry, University of Geneva, Switzerland.

出版信息

Comput Appl Biosci. 1996 Dec;12(6):507-10. doi: 10.1093/bioinformatics/12.6.507.

DOI:10.1093/bioinformatics/12.6.507

PMID:9021269

Abstract

LALNVIEW is a graphical program for visualising local alignments between two sequences (protein or nucleic acids). Sequences are represented by coloured rectangles to give an overall picture of their similarities. LALNVIEW can display sequence features (exon, intron, active site, domain, propeptide, etc.) along with the alignment. When using LALNVIEW through our Web servers, sequence features are automatically extracted from database annotations (SWISS-PROT, GenBank, EMBL or HOVERGEN) and displayed with the alignment. LALNVIEW is a useful tool for analysing pairwise sequence alignments and for making the link between sequence homology and what is known about the structure or function of sequences. LALNVIEW executables for UNIX, Macintosh and PC computers are freely available from our server (http:// expasy.hcuge.ch/sprot/lalnview.html).

摘要

LALNVIEW是一个用于可视化两个序列（蛋白质或核酸）之间局部比对的图形程序。序列由彩色矩形表示，以给出它们相似性的整体图景。LALNVIEW可以在比对的同时显示序列特征（外显子、内含子、活性位点、结构域、前肽等）。通过我们的网络服务器使用LALNVIEW时，序列特征会自动从数据库注释（SWISS-PROT、GenBank、EMBL或HOVERGEN）中提取，并与比对结果一起显示。LALNVIEW是分析成对序列比对以及在序列同源性与已知的序列结构或功能之间建立联系的有用工具。适用于UNIX、Macintosh和PC计算机的LALNVIEW可执行文件可从我们的服务器（http:// expasy.hcuge.ch/sprot/lalnview.html）免费获取。