Multicystic kidney in siblings.

Two siblings (one girl and one boy), with a left multicystic kidney in whom a renal abnormality had been recognized prenatally, are reported. A large renal mass was present in both patients and the second sibling also had hypertension. Early surgical resection was carried out with satisfactory clinical progress and resolution of the hypertension. Multicystic kidney is considered a developmental abnormality with a sporadic incidence. These cases and other reports of familial incidence in the literature indicate that there may also be a genetic basis for the abnormality.