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围生期检测到的多囊性发育不良肾的管理

[Management of multicystic dysplastic kidney detected in perinatal periods].

作者信息

Tohda A, Hosokawa S, Shimada K

机构信息

Division of Urology, Osaka Medical Center.

出版信息

Nihon Hinyokika Gakkai Zasshi. 1992 Oct;83(10):1628-32. doi: 10.5980/jpnjurol1989.83.1628.

Abstract

We analyzed 17 cases of multicystic dysplastic kidney (MCDK) to document the natural history of MCDK and its management. One patient was nephrectomied for respiratory failure associated with MCDK. Follow-up studies of 14 kidneys revealed that 5 kidneys (36%) did not change in size, 7 kidneys (50%) decreased in size. Two kidneys (14%) increased in size during the follow up periods and were nephrectomized. Hypertension and malignancy was not observed in our cases. Evaluations for the contralateral kidney and urinary tract system were performed in 15 patients and 5 (33%) revealed abnormalities--two patients with VUR, 1 with PUJ stenosis, 1 with ureteral stricture and 1 with ectopic ureterocele. In our hospital, the management for MCDK is conservative in most cases. Nephrectomy is indicated when there are complications resulting from the size of MCDK, or when the kidney continues to increase in size after the second year of life.

摘要

我们分析了17例多囊性发育不良肾(MCDK),以记录MCDK的自然病程及其处理方法。1例患者因与MCDK相关的呼吸衰竭而接受了肾切除术。对14个肾脏的随访研究显示,5个肾脏(36%)大小未变,7个肾脏(50%)体积缩小。2个肾脏(14%)在随访期间体积增大并接受了肾切除术。我们的病例中未观察到高血压和恶性肿瘤。对15例患者的对侧肾脏和泌尿系统进行了评估,5例(33%)发现异常——2例患者有膀胱输尿管反流(VUR),1例有肾盂输尿管连接部(PUJ)狭窄,1例有输尿管狭窄,1例有异位输尿管囊肿。在我们医院,大多数情况下对MCDK的处理是保守的。当MCDK的大小导致并发症,或在生命的第二年之后肾脏继续增大时,建议进行肾切除术。

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