Insulin and the arginine paradox.
作者信息
Kurz S, Harrison D G
出版信息
J Clin Invest. 1997 Feb 1;99(3):369-70. doi: 10.1172/JCI119166.
Abstract
摘要
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Insulin and the arginine paradox.胰岛素与精氨酸悖论。
J Clin Invest. 1997 Feb 1;99(3):369-70. doi: 10.1172/JCI119166.
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The effects of a comparatively higher dose of 1000 mg/kg/d of oral L- or D-arginine on the L-arginine metabolic pathways in male Sprague-Dawley rats.比较高剂量的 1000 毫克/公斤/天的口服 L-或 D-精氨酸对雄性 Sprague-Dawley 大鼠的 L-精氨酸代谢途径的影响。
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本文引用的文献
1
The vascular effects of L-Arginine in humans. The role of endogenous insulin.L-精氨酸对人体的血管作用。内源性胰岛素的作用。
J Clin Invest. 1997 Feb 1;99(3):433-8. doi: 10.1172/JCI119177.
2
Effect of asymmetric dimethyl arginine on nitric oxide synthase activity in normal and pre-eclamptic placentae.不对称二甲基精氨酸对正常及子痫前期胎盘组织中一氧化氮合酶活性的影响。
Reprod Fertil Dev. 1995;7(6):1581-4. doi: 10.1071/rd9951581.
3
Acylation targets emdothelial nitric-oxide synthase to plasmalemmal caveolae.酰化作用将内皮型一氧化氮合酶靶向至质膜小窝。
J Biol Chem. 1996 Mar 15;271(11):6518-22. doi: 10.1074/jbc.271.11.6518.
4
Elevated L-arginine/dimethylarginine ratio contributes to enhanced systemic NO production by dietary L-arginine in hypercholesterolemic rabbits.在高胆固醇血症兔中，升高的L-精氨酸/二甲基精氨酸比值有助于膳食L-精氨酸增强全身一氧化氮的生成。
Biochem Biophys Res Commun. 1996 Feb 15;219(2):598-603. doi: 10.1006/bbrc.1996.0279.
5
Insulin-mediated skeletal muscle vasodilation is nitric oxide dependent. A novel action of insulin to increase nitric oxide release.胰岛素介导的骨骼肌血管舒张依赖于一氧化氮。胰岛素增加一氧化氮释放的一种新作用。
J Clin Invest. 1994 Sep;94(3):1172-9. doi: 10.1172/JCI117433.
6
Hemodynamic actions of insulin.胰岛素的血流动力学作用。
Am J Physiol. 1994 Aug;267(2 Pt 1):E187-202. doi: 10.1152/ajpendo.1994.267.2.E187.
7
Interactions between L-arginine and L-glutamine change endothelial NO production. An effect independent of NO synthase substrate availability.L-精氨酸与L-谷氨酰胺之间的相互作用会改变内皮细胞一氧化氮的生成。这是一种独立于一氧化氮合酶底物可用性的效应。
J Clin Invest. 1995 Jun;95(6):2565-72. doi: 10.1172/JCI117957.
8
Vascular endothelial cells synthesize nitric oxide from L-arginine.血管内皮细胞从L-精氨酸合成一氧化氮。
Nature. 1988 Jun 16;333(6174):664-6. doi: 10.1038/333664a0.
9
L-arginine does not restore endothelial dysfunction in atherosclerotic rabbit aorta in vitro.
Blood Vessels. 1991;28(5):354-7. doi: 10.1159/000158881.
10
Accumulation of an endogenous inhibitor of nitric oxide synthesis in chronic renal failure.
Lancet. 1992 Mar 7;339(8793):572-5. doi: 10.1016/0140-6736(92)90865-z.
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