放疗中丙氨酸剂量测定的一年经验。
One year of experience with alanine dosimetry in radiotherapy.
作者信息
Schaeken B, Scalliet P
机构信息
A. Z. Middelheim, Department of Radiotherapy, Antwerp, Belgium.
出版信息
Appl Radiat Isot. 1996 Nov-Dec;47(11-12):1177-82. doi: 10.1016/s0969-8043(96)00040-1.
Commercially available alanine dosimeters from different manufacturers were purchased for this study. The response of the detectors was evaluated with 60Co gamma radiation in the dose range 0.2-200 Gy, using a small EPR spectrometer dedicated to dosimetry. The batch sensitivity, inter-specimen scattering and background signal for the different selection of dosimeters were evaluated. The usefulness of the alanine dosimetry system for clinical routine is illustrated by in vivo measurements during 192Ir brachytherapy of cervix carcinoma.
本研究购买了不同制造商生产的市售丙氨酸剂量计。使用专门用于剂量测定的小型电子顺磁共振光谱仪，在0.2 - 200 Gy的剂量范围内，用⁶⁰Coγ射线评估探测器的响应。评估了不同剂量计选择的批次灵敏度、样本间散射和背景信号。通过宫颈癌¹⁹²Ir近距离治疗期间的体内测量，说明了丙氨酸剂量测定系统在临床常规中的实用性。
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