宫颈细胞学筛查中的质量保证。快速重新筛查与PAPNET检测系统的比较。
Quality assurance in cervical cytology screening. Comparison of rapid rescreening and the PAPNET Testing System.
作者信息
Halford J A, Wright R G, Ditchmen E J
机构信息
Department of Anatomical Pathology, Queensland Medical Laboratory, Brisbane, Australia.
出版信息
Acta Cytol. 1997 Jan-Feb;41(1):79-81. doi: 10.1159/000332309.
OBJECTIVE
To assess the performance of the PAPNET Testing System and compare the sensitivity of this automated device with that of rapid rescreening.
STUDY DESIGN
In this study, 1,000 cervical smears previously diagnosed by our laboratory as negative were seeded with 20 particularly "difficult" cases. We submitted this seeded set of smears for rapid rescreening and to PAPNET to determine cases that could be detected by rapid rescreening, PAPNET or both.
RESULTS
Rapid rescreening detected 9 of the 20 cases (45%). The PAPNET system identified 19/20 (95%). This investigation found PAPNET rescreening to be more effective than rapid rescreening in detecting the seeded difficult cases.
CONCLUSION
Use of the PAPNET Testing System in tandem with rapid rescreening can reduce the rate of false negatives in diagnostically difficult cervical cytologic smears.
目的
评估PAPNET检测系统的性能，并将这种自动化设备的敏感性与快速复查的敏感性进行比较。
研究设计
在本研究中，我们在1000份先前经本实验室诊断为阴性的宫颈涂片样本中加入了20例特别“难检”的病例。我们将这组接种后的涂片送去进行快速复查和PAPNET检测，以确定哪些病例可通过快速复查、PAPNET检测或两者同时检测出来。
结果
快速复查检测出了20例中的9例（45%）。PAPNET系统识别出了19/20例（95%）。本研究发现，在检测接种的难检病例方面，PAPNET复查比快速复查更有效。
结论
将PAPNET检测系统与快速复查联合使用，可以降低诊断困难的宫颈细胞学涂片的假阴性率。
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