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TracCell系统在巴氏染色细胞学材料绘图中的应用

Utility of the TracCell system in mapping Papanicolaou-stained cytologic material.

作者信息

Grohs D H, Dadeshidze V V, Domanik R A, Gombrich P P, Olsson L J, Pressman N J

机构信息

AccuMed International, Inc., Chicago, Illinois 60610, USA.

出版信息

Acta Cytol. 1997 Jan-Feb;41(1):144-52. doi: 10.1159/000332316.

DOI:10.1159/000332316
PMID:9022737
Abstract

BACKGROUND

Much attention has been directed toward commercial application of automation technology to support both quality and productivity enhancement in cervical cytology screening. The introduction of a fully automated precision microscopy workstation, the AcCell Series 2000, (Accu-Med International, Inc., Chicago, Illinois, U.S.A.) has made it possible to effectively incorporate automated prescreening systems that support the human screener.

SYSTEM DESIGN

The TracCell 2000 slide mapping system (AccuMed) is a fully automated, stand-alone prescreening device for Papani-colaou-stained cytologic material, such as cervical cytology specimens. The system locates the areas of the slide that do not require review and maps material in the remaining areas; it finds the optimal focal plane, calculates a preferred routing path for human review and determines speed adjustment relative to material density variation. Through slide bar coding identification, this information is transmitted to the AcCell precision microscopy workstation for presentation of the specimen to the human screener.

DISCUSSION

By making it possible to automatically guide the human screener to the material of interest, the TracCell system eliminates the need to review empty space and irrelevant areas of the slide. This has the immediate advantage of improved productivity. In addition, by reducing the need to review neutral background material, the system increases the signal-to-noise ratio, thus contributing to a sustained level of vigilance in the screener. The system also addresses operator fatigue through computer-assisted focus and speed variation. This instrument is for investigational use only. The performance characteristics of the device have not been established.

摘要

背景

自动化技术在宫颈细胞学筛查中对提高质量和生产力的商业应用已备受关注。全自动精密显微镜工作站AcCell Series 2000(美国伊利诺伊州芝加哥市Accu-Med International公司)的推出,使得有效整合支持人工筛查员的自动预筛查系统成为可能。

系统设计

TracCell 2000玻片映射系统(AccuMed公司)是一种全自动的独立预筛查设备,用于巴氏染色的细胞学材料,如宫颈细胞学标本。该系统可定位玻片上无需检查的区域,并对其余区域的材料进行映射;它能找到最佳焦平面,计算出人工检查的首选路径,并根据材料密度变化确定速度调整。通过玻片条形码识别,该信息被传输到AcCell精密显微镜工作站,以便将标本呈现给人工筛查员。

讨论

通过能够自动引导人工筛查员关注感兴趣的材料,TracCell系统消除了检查玻片空白区域和无关区域的需要。这直接提高了生产力。此外,通过减少检查中性背景材料的需求,该系统提高了信噪比,从而有助于筛查员保持持续的警惕性。该系统还通过计算机辅助聚焦和速度变化来解决操作员疲劳问题。本仪器仅用于研究。该设备的性能特征尚未确定。

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