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南非实验小鼠中特定病毒抗体的调查。

Survey for antibodies to selected viruses in laboratory mice in South Africa.

作者信息

Van Vuuren M, De Klerk W A, De Beer M C, Van Niekerk T A

机构信息

Department of Infectious Diseases and Public Health, Faculty of Veterinary Science, Medical University of Southern Africa, Medunsa, Republic of South Africa.

出版信息

J S Afr Vet Assoc. 1990 Dec;61(4):174-5.

PMID:9022849
Abstract

Serum samples (n = 184) from 3 conventional laboratory mouse colonies were tested for antibodies with an indirect fluorescent antibody (IFA) test to Theiler's murine encephalomyelitis virus (TMEV), encephalomyocarditis virus (EMCV), and reovirus Type 3. The percentage of mice with antibodies to reovirus Type 3, were comparable in all 3 groups, namely 40, 46 and 60%. Antibodies to TMEV showed the greatest variation, namely 0, 10 and 31%, whereas antibodies to EMCV were confirmed in only one colony (7%). In addition, 98 serum samples from 2 other colonies yielded 69% animals positive for rotavirus with the IFA test.

摘要

对来自3个传统实验小鼠种群的血清样本(n = 184)进行检测,采用间接荧光抗体(IFA)试验检测抗泰勒氏鼠脑脊髓炎病毒(TMEV)、脑心肌炎病毒(EMCV)和呼肠孤病毒3型的抗体。3组小鼠中抗呼肠孤病毒3型抗体的百分比相当,分别为40%、46%和60%。抗TMEV抗体的变化最大,分别为0%、10%和31%,而抗EMCV抗体仅在一个种群中得到确认(7%)。此外,来自其他2个种群的98份血清样本经IFA试验检测,69%的动物轮状病毒呈阳性。

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