Miller N J, Johnston J D, Collis C S, Rice-Evans C
Division of Biochemistry and Molecular Biology, United Medical School, Guy's Hospital, London, UK.
Ann Clin Biochem. 1997 Jan;34 ( Pt 1):85-90. doi: 10.1177/000456329703400113.
Serum total antioxidant activity (TAA), albumin and uric acid were measured on admission, and for the next 2 days in 56 patients suffering myocardial infarction, 20 of whom received streptokinase. The 'antioxidant gap', the difference between the serum TAA and the sum of the serum albumin and uric acid activity, was calculated. No significant changes in serum total antioxidant activity were observed in either group of patients between admission, day 1 and day 2. However, a decline in the 'antioxidant gap' after myocardial infarction was associated with a significantly higher mortality.
对56例心肌梗死患者入院时及随后2天测定血清总抗氧化活性（TAA）、白蛋白和尿酸，其中20例接受链激酶治疗。计算“抗氧化剂差距”，即血清TAA与血清白蛋白和尿酸活性之和的差值。两组患者在入院、第1天和第2天之间血清总抗氧化活性均未观察到显著变化。然而，心肌梗死后“抗氧化剂差距”的下降与显著更高的死亡率相关。
