义齿用玻璃纤维-聚甲基丙烯酸甲酯复合材料中残留甲基丙烯酸甲酯向水中的释放。

Release of residual methyl methacrylate into water from glass fibre-poly(methyl methacrylate) composite used in dentures.

作者信息

Miettinen V M, Vallittu P K

机构信息

Department of Oral Pathology, University of Kuopio, Finland.

出版信息

Biomaterials. 1997 Jan;18(2):181-5. doi: 10.1016/s0142-9612(96)00123-8.

DOI:10.1016/s0142-9612(96)00123-8

PMID:9022967

Abstract

The aim of this study was to determine the release of residual methyl methacrylate (MMA) into water from heat-cured and chemical-cured test specimens of continuous glass fibre-poly(methyl methacrylate) (PMMA) composite fabricated from experimental glass fibre reinforcement. The glass fibre concentration of the test specimens was 12% by weight. The residual MMA was extracted from the storage water of the test specimens (n = 5 per group) and its concentration was determined by high-performance liquid chromatography. The results revealed that release of residual MMA from heat-cured test specimens with glass fibre reinforcement was significantly higher than that from unreinforced test specimens (P = 0.003), while in chemical-cured test specimens with and without glass fibre reinforcement the amount of MMA released did not differ (P = 0.501). In general, however the test specimens made from chemical-cured PMMA released more residual MMA than specimens made from heat-cured PMMA (P < 0.001). This study suggests that the use of glass fibre reinforcement in heat-cured denture PMMA statistically increases the release of residual MMA from the material, but it is questionable whether it has clinical significance.

摘要

本研究的目的是测定由实验性玻璃纤维增强材料制成的连续玻璃纤维 - 聚甲基丙烯酸甲酯（PMMA）复合材料的热固化和化学固化测试样本中残留甲基丙烯酸甲酯（MMA）向水中的释放情况。测试样本的玻璃纤维浓度为12%（重量）。从测试样本的储存水中提取残留的MMA（每组n = 5），并通过高效液相色谱法测定其浓度。结果显示，有玻璃纤维增强的热固化测试样本中残留MMA的释放量显著高于未增强的测试样本（P = 0.003），而在有和没有玻璃纤维增强的化学固化测试样本中，MMA的释放量没有差异（P = 0.501）。然而，总体而言，化学固化PMMA制成的测试样本比热固化PMMA制成的样本释放更多的残留MMA（P < 0.001）。本研究表明，在热固化义齿PMMA中使用玻璃纤维增强材料在统计学上会增加材料中残留MMA的释放，但它是否具有临床意义仍值得怀疑。