Mohan K, Kelly P J, Hill F W, Muvavarirwa P, Pawandiwa A
Faculty of Veterinary Science, University of Zimbabwe, Harare, Zimbabwe.
Comp Immunol Microbiol Infect Dis. 1997 Jan;20(1):29-34. doi: 10.1016/s0147-9571(96)00029-x.
A variety of disease manifestations, comprising skin bite wounds, pyothorax, respiratory and genitourinary tract infections, in 202 dogs and cats presented to the University Clinic, were investigated for the presence of Pasteurella multocida. Of these, 25-42% of various cases (69) were found to be infected with P. multocida. P. multocida-associated respiratory tract infections were more common than bite wounds or genitourinary tract infections. The regimen of treatment consisted of those antibiotics, sensitivity to which had been confirmed in vitro. Following detailed characterization of the isolates of P. multocida, in order to assign them to the reclassified taxa of Pasteurella, a preponderance of P. multocida subspecies multocida and septica were recorded. There did not appear to be a correlation between the reclassified taxa and their serotypes. Certain strains of different species or subspecies belonged to a common serotype and vice versa. However, the strains which were serotyped belonged to capsular type A, except for a solitary isolate from a cat which was capsular type D. Type D is known to cause atrophic rhinitis and does not appear to have been isolated either from a dog or a cat. Two strains, one from a dog and another from a cat, were identified as group EF-4 bacteria. This group of organisms has been incriminated in human wounds resulting from dog/cat bites, and has so far not been reported in Africa. Three different species, P. stomatis, P. dagmatis and P. multocida subspecies multocida were simultaneously isolated from a case of chronic bronchitis in a dog. There was no evidence of any relationship between disease manifestation in a host and the isolation of a particular taxon of Pasteurella, except that P. canis and Pasteurella taxon 16 were only isolated from dogs.
对送至大学诊所的202只犬猫身上出现的各种疾病表现（包括皮肤咬伤伤口、脓胸、呼吸道和泌尿生殖道感染）进行了多杀性巴氏杆菌感染情况调查。其中，在各类病例（69例）中有25%-42%被发现感染了多杀性巴氏杆菌。多杀性巴氏杆菌相关的呼吸道感染比咬伤伤口或泌尿生殖道感染更为常见。治疗方案采用那些在体外已证实有敏感性的抗生素。在对多杀性巴氏杆菌分离株进行详细鉴定以将它们归入重新分类的巴氏杆菌分类单元后，记录到多杀性巴氏杆菌多杀亚种和败血亚种占优势。重新分类的分类单元与其血清型之间似乎没有相关性。不同种或亚种的某些菌株属于同一血清型，反之亦然。然而，除了一只猫的单个分离株为D型荚膜外，分型的菌株均属于A 型荚膜。已知D型会引起萎缩性鼻炎，似乎尚未从犬或猫中分离到。从一只犬的慢性支气管炎病例中同时分离出三种不同的菌种，即口腔巴氏杆菌、犬咬巴氏杆菌和多杀性巴氏杆菌多杀亚种。除了犬巴斯德菌和巴氏杆菌分类单元16仅从犬中分离到外，没有证据表明宿主中的疾病表现与特定巴氏杆菌分类单元的分离之间存在任何关系。
