Simpson R H, Skálová A
Postgraduate Medical School, University of Exeter, UK.
Histopathology. 1997 Jan;30(1):70-4. doi: 10.1046/j.1365-2559.1997.d01-563.x.
Two patients are described in each of whom metastatic prostatic carcinoma presented as a tumour of the parotid gland. In one, primary prostate cancer had been diagnosed three years prior to the appearance of what was believed clinically to be an unrelated salivary lesion. In the other a neck swelling was the first indication of disease, although subsequent investigation revealed widespread metastases. Biopsy of each tumour showed an adenocarcinoma with immunohistochemical expression of prostate markers. These cases, and the six previous reports, illustrate the need to consider metastatic carcinoma from the prostate in the assessment of any malignant tumour of the salivary glands in men of advancing years.
本文描述了两名患者，他们均表现为腮腺肿瘤，经诊断为转移性前列腺癌。其中一名患者，在临床诊断为不相关的唾液腺病变出现三年前，已确诊为原发性前列腺癌。另一名患者颈部肿胀是疾病的首发症状，尽管后续检查发现已有广泛转移。对每个肿瘤进行活检，均显示为腺癌，且前列腺标志物呈免疫组化表达。这些病例以及之前的六篇报道表明，在评估老年男性唾液腺的任何恶性肿瘤时，都需要考虑前列腺来源的转移性癌。
