抗甜味天然产物。十二。来自琉球马利筋日本变种的西他基糖苷XI - XX的结构。

Antisweet natural products. XII. Structures of sitakisosides XI-XX from Stephanotis lutchuensis Koidz. var. japonica.

作者信息

Yoshikawa K, Mizutani A, Kan Y, Arihara S

机构信息

Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Japan.

出版信息

Chem Pharm Bull (Tokyo). 1997 Jan;45(1):62-7. doi: 10.1248/cpb.45.62.

DOI:10.1248/cpb.45.62

PMID:9023968

Abstract

From the fresh stem of Stephanotis lutchuensis var. japonica, ten new oleanane-type triterpenoid glycosides, named sitakisosides XI-XX (1-10), were isolated. Their structures were determined on the basis of spectroscopic data and chemical evidence. The results show that all have a 3-O-beta-D-xylopyranosyl(1 --> 6)-beta-D-glucopyranosyl(1 --> 6)- beta-D-glucopyranosyl moiety and the aglycones of sitakisosides XI-XV, XVI and XVII, XVIII and XIX, and XX are sitakisogenin, chichipegenin, marsglobiferin and longispinogenin, respectively. Sitakisosides XI-XIII, XVI and XVIII, having an acyl group, showed antisweet activity.

摘要

从琉球马利筋变种日本马利筋的新鲜茎中，分离出了10种新的齐墩果烷型三萜糖苷，命名为喜太皂苷XI - XX（1 - 10）。它们的结构是根据光谱数据和化学证据确定的。结果表明，所有化合物都具有一个3 - O - β - D - 吡喃木糖基（1→6）- β - D - 吡喃葡萄糖基（1→6）- β - D - 吡喃葡萄糖基部分，喜太皂苷XI - XV、XVI和XVII、XVIII和XIX以及XX的苷元分别为喜太皂苷元、奇奇佩皂苷元、马尔斯球皂苷元和长刺皂苷元。具有酰基的喜太皂苷XI - XIII、XVI和XVIII表现出抗甜味活性。