细胞周期蛋白依赖性激酶与果蝇细胞周期
Cdks and the Drosophila cell cycle.
作者信息
Follette P J, O'Farrell P H
机构信息
Department of Biochemistry & Biophysics, University of California San Francisco, California 94143-0448 USA.
出版信息
Curr Opin Genet Dev. 1997 Feb;7(1):17-22. doi: 10.1016/s0959-437x(97)80104-9.
Abstract
Cyclin-dependent kinases play essential roles in driving the cell cycle. Much progress has been made in Drosophila over the past year in identifying the specific requirements for individual cyclins in particular cell cycle events. These studies encompass many aspects of the cell cycle, from the addition of a G1 phase to the cell cycle during embryogenesis to the role of cyclin degradation in progression through anaphase.
摘要
细胞周期蛋白依赖性激酶在驱动细胞周期中发挥着至关重要的作用。过去一年里，在果蝇研究中，对于特定细胞周期事件中各个细胞周期蛋白的具体需求的识别取得了很大进展。这些研究涵盖了细胞周期的许多方面，从胚胎发育过程中细胞周期增加一个G1期到细胞周期蛋白降解在后期进程中的作用。
相似文献
1
Cdks and the Drosophila cell cycle.细胞周期蛋白依赖性激酶与果蝇细胞周期
Curr Opin Genet Dev. 1997 Feb;7(1):17-22. doi: 10.1016/s0959-437x(97)80104-9.
2
A breath of fresh air for cyclin D/Cdk4: triggering growth via Hph.细胞周期蛋白D/细胞周期蛋白依赖性激酶4的一股清新之风：通过Hph触发生长。
Dev Cell. 2004 Feb;6(2):163-4. doi: 10.1016/s1534-5807(04)00031-0.
3
CDKs and cyclins in transition(s).细胞周期转换中的细胞周期蛋白依赖性激酶和细胞周期蛋白
Curr Opin Genet Dev. 1997 Feb;7(1):32-8. doi: 10.1016/s0959-437x(97)80106-2.
4
Drosophila Cdk4 is required for normal growth and is dispensable for cell cycle progression.果蝇Cdk4是正常生长所必需的，而对于细胞周期进程则是非必需的。
EMBO J. 2000 Sep 1;19(17):4533-42. doi: 10.1093/emboj/19.17.4533.
5
The driving power of the cell cycle: cyclin-dependent kinases, cyclins and their inhibitors.细胞周期的驱动力量：细胞周期蛋白依赖性激酶、细胞周期蛋白及其抑制剂。
Bratisl Lek Listy. 2023;124(4):261-266. doi: 10.4149/BLL_2023_039.
6
The emerging roles of the CDK/cyclin complexes in antiviral innate immunity.CDK/周期蛋白复合物在抗病毒先天免疫中的新兴作用。
J Med Virol. 2022 Jun;94(6):2384-2387. doi: 10.1002/jmv.27554. Epub 2022 Jan 7.
7
Cyclins and CDKS in development and cancer: lessons from genetically modified mice.细胞周期蛋白和细胞周期蛋白依赖性激酶在发育与癌症中的作用：来自基因编辑小鼠的启示
Front Biosci. 2006 Jan 1;11:1164-88. doi: 10.2741/1871.
8
Antiproliferative action of valproate is associated with aberrant expression and nuclear translocation of cyclin D3 during the C6 glioma G1 phase.丙戊酸盐的抗增殖作用与C6胶质瘤G1期细胞周期蛋白D3的异常表达及核转位有关。
J Neurochem. 2002 Oct;83(1):12-9. doi: 10.1046/j.1471-4159.2002.01081.x.
9
Cell Cycle Progression and Synchronization: An Overview.细胞周期进程和同步：概述。
Methods Mol Biol. 2022;2579:3-23. doi: 10.1007/978-1-0716-2736-5_1.
10
The endoplasmic reticulum takes center stage in cell cycle regulation.内质网在细胞周期调控中占据核心地位。
Sci Signal. 2008 Jan 22;1(3):pe4. doi: 10.1126/stke.13pe4.
引用本文的文献
1
From egg to gastrula: how the cell cycle is remodeled during the Drosophila mid-blastula transition.从卵到原肠胚：果蝇中囊胚转换过程中细胞周期是如何重塑的。
Annu Rev Genet. 2014;48:269-94. doi: 10.1146/annurev-genet-111212-133531. Epub 2014 Sep 5.
2
The Drosophila F-box protein dSkp2 regulates cell proliferation by targeting Dacapo for degradation.果蝇 F-box 蛋白 dSkp2 通过靶向 Dacapo 进行降解来调节细胞增殖。
Mol Biol Cell. 2013 Jun;24(11):1676-87, S1-7. doi: 10.1091/mbc.E12-10-0772. Epub 2013 Apr 3.
3
Cardiac progenitors and the embryonic cell cycle.心脏祖细胞与胚胎细胞周期。
Cell Cycle. 2007 Aug 15;6(16):1974-81. doi: 10.4161/cc.6.16.4584. Epub 2007 Jun 13.
4
The schedule of destruction of three mitotic cyclins can dictate the timing of events during exit from mitosis.三种有丝分裂周期蛋白的降解时间表能够决定有丝分裂退出过程中各个事件的发生时间。
Curr Biol. 2001 May 1;11(9):671-83. doi: 10.1016/s0960-9822(01)00204-4.
5
Identification of novel Drosophila meiotic genes recovered in a P-element screen.在P因子筛选中发现的新型果蝇减数分裂基因的鉴定。
Genetics. 1999 Jun;152(2):529-42. doi: 10.1093/genetics/152.2.529.
6
Exit from mitosis in Drosophila syncytial embryos requires proteolysis and cyclin degradation, and is associated with localized dephosphorylation.果蝇合胞体胚胎中从有丝分裂退出需要蛋白水解作用和细胞周期蛋白降解，并且与局部去磷酸化有关。
Genes Dev. 1998 May 15;12(10):1495-503. doi: 10.1101/gad.12.10.1495.
7
Cell cycle control of chorion gene amplification.绒毛膜基因扩增的细胞周期调控
Genes Dev. 1998 Mar 1;12(5):734-44. doi: 10.1101/gad.12.5.734.
8
Cdk7 is essential for mitosis and for in vivo Cdk-activating kinase activity.细胞周期蛋白依赖性激酶7（Cdk7）对于有丝分裂和体内Cdk激活激酶活性至关重要。
Genes Dev. 1998 Feb 1;12(3):370-81. doi: 10.1101/gad.12.3.370.
9
Connecting cell behavior to patterning: lessons from the cell cycle.将细胞行为与模式形成联系起来：细胞周期的启示。
Cell. 1997 Feb 7;88(3):309-14. doi: 10.1016/s0092-8674(00)81869-3.
本文引用的文献
1
Cell cycle control: many ways to skin a cat.细胞周期调控：条条大路通罗马。
Trends Cell Biol. 1992 Jun;2(6):159-63. doi: 10.1016/0962-8924(92)90034-k.
2
A cyclin-dependent kinase inhibitor, Dacapo, is necessary for timely exit from the cell cycle during Drosophila embryogenesis.细胞周期蛋白依赖性激酶抑制剂Dacapo在果蝇胚胎发育过程中对于及时退出细胞周期是必需的。
Cell. 1996 Dec 27;87(7):1237-47. doi: 10.1016/s0092-8674(00)81819-x.
3
Dacapo, a cyclin-dependent kinase inhibitor, stops cell proliferation during Drosophila development.达卡波（Dacapo）是一种细胞周期蛋白依赖性激酶抑制剂，在果蝇发育过程中会阻止细胞增殖。
Cell. 1996 Dec 27;87(7):1225-35. doi: 10.1016/s0092-8674(00)81818-8.
4
The role of proteolysis in cell cycle progression in Schizosaccharomyces pombe.蛋白水解在粟酒裂殖酵母细胞周期进程中的作用。
EMBO J. 1996 Oct 1;15(19):5268-79.
5
The Drosophila endocycle is controlled by Cyclin E and lacks a checkpoint ensuring S-phase completion.果蝇的内复制周期由细胞周期蛋白E控制，并且缺乏确保S期完成的检查点。
Genes Dev. 1996 Oct 1;10(19):2514-26. doi: 10.1101/gad.10.19.2514.
6
E2F-induced S phase requires cyclin E.E2F诱导的S期需要细胞周期蛋白E。
Genes Dev. 1996 Oct 1;10(19):2505-13. doi: 10.1101/gad.10.19.2505.
7
RBF, a novel RB-related gene that regulates E2F activity and interacts with cyclin E in Drosophila.RBF是一种新的与RB相关的基因，它在果蝇中调节E2F活性并与细胞周期蛋白E相互作用。
Genes Dev. 1996 May 15;10(10):1206-18. doi: 10.1101/gad.10.10.1206.
8
Ectopic expression of dE2F and dDP induces cell proliferation and death in the Drosophila eye.dE2F和dDP的异位表达在果蝇眼睛中诱导细胞增殖和死亡。
EMBO J. 1996 Jul 15;15(14):3684-92.
9
Ectopic E2F expression induces S phase and apoptosis in Drosophila imaginal discs.异位E2F表达诱导果蝇成虫盘进入S期并引发凋亡。
Genes Dev. 1996 Jun 1;10(11):1422-32. doi: 10.1101/gad.10.11.1422.
10
A Cdc2 dependent checkpoint maintains diploidy in Drosophila.
Development. 1996 Apr;122(4):1051-8. doi: 10.1242/dev.122.4.1051.
Zotero 插件