Chromogenic lactate-leukocyte esterase substrates.
作者信息
Johnson G M, Schaeper R
机构信息
Diagnostics Division, Bayer Corporation, Elkhart, Indiana 46515, USA.
出版信息
Bioconjug Chem. 1997 Jan-Feb;8(1):76-80. doi: 10.1021/bc960081h.
PMID:9026039
Abstract
The first successful reported use of lactate-based chromogenic, colorimetric substrates for a serine protease-based enzyme is described. A series of hydroxy-protected 5-phenyl-3-hydroxypyrrolyl L-lactate substrates of the general formula RO-Lac-OPP were prepared and formulated into reagents for the determination of leukocytes in dry phase formats.
摘要
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