Mozharov O T, Savostina E P, Anisimov P I, Shvedun G P, Popov Iu A
Genetika. 1996 Sep;32(9):1176-83.
A conceptual model of the Yersinia pestis Ca(2+)-dependence mechanism is proposed. The model is based on data from analyses of peculiarities of recombinant cells of this plague-causing agent carrying the cloned first Bg/II fragment of the Ca(2+)-dependence plasmid (pCaD) and a combination of this fragment and other plasmid pCaD fragments. The data obtained also allowed a revision of the role of the lcr GVH locus of pCaD in this phenomenon.
提出了鼠疫耶尔森菌钙依赖性机制的概念模型。该模型基于对携带钙依赖性质粒(pCaD)克隆的首个Bg/II片段的这种致病鼠疫菌重组细胞特性分析的数据,以及该片段与其他质粒pCaD片段组合的数据。所获得的数据还使得对pCaD的lcr GVH基因座在这一现象中的作用有了新的认识。