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[个体发育过程中颌牙异常发生发展的基因型和表型因素相互作用分析]

[Analysis of the interaction of genotypic and paratypic factors in the development of maxillo-dental anomalies in ontogeny].

作者信息

Lil'in E T, Persin L S, Titov V I, Danilina O A

出版信息

Genetika. 1996 Sep;32(9):1295-8.

PMID:9026469
Abstract

Component analysis of total phenotypic variance was used to analyze data on 80 pairs of twins aged 3 to 18 years, examined in the Stupino outpatient dental clinic, Moscow oblast. Genotypic and environmental factors are shown to play different roles in the development of abnormalities of teeth, dental arches, and occlusion at different ontogenetic periods of deciduous, mixed, and permanent dentition. Periods when paratypic factors prevailed were revealed. This made it possible to identity periods when prophylaxis and orthodontic treatment are the most advisable.

摘要

采用总表型方差的成分分析方法,对在莫斯科州斯图皮诺门诊牙科诊所接受检查的80对3至18岁双胞胎的数据进行了分析。结果表明,在乳牙期、混合牙列期和恒牙列期的不同个体发育阶段,基因型和环境因素在牙齿、牙弓及咬合异常的发生发展中发挥着不同作用。研究发现了副型因素占主导的时期。这使得确定预防和正畸治疗最适宜的时期成为可能。

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