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82对女性双胞胎牙齿性状的遗传分析。

Genetic analysis of dental traits in 82 pairs of female-female twins.

作者信息

Liu H, Deng H, Cao C F, Ono H

机构信息

Department of Pediatric Dentistry, School of Stomatology, Beijing Medical University (BMU), P. R. China.

出版信息

Chin J Dent Res. 1998 Dec;1(3):12-6.

PMID:10557166
Abstract

OBJECTIVE

To study systematically the heritability of dental traits.

METHODS

Eighty-two pairs of female-female twins from 6 to 12 years old were collected. Twin zygosity diagnosis was made by DNA fingerprinting. The study was composed of questionnaires, oral examinations, model measurements, and panoramic radiographs. The same analytic method was used for each of the dental traits and comparison of their heritability was made.

RESULTS AND CONCLUSIONS

According to the significance of difference and the level of heritability, the dental traits were divided into four types: strong, median, weak, and weaker heritability. The number of third molars present, tooth size, arch size, and upper lateral incisor malformation were under strong genetic influence; hypodontia indicated a median heritability; a weak heritability was seen in tooth eruption and caries, and a weaker heritability was found in occlusal traits. The division made it easy to learn the genetic characteristics of dental traits systematically and supplemented the theory of dental genetics.

摘要

目的

系统研究牙齿性状的遗传度。

方法

收集82对6至12岁的女性双胞胎。通过DNA指纹图谱进行双胞胎合子性诊断。该研究包括问卷调查、口腔检查、模型测量和全景X线片。对每个牙齿性状采用相同的分析方法,并对其遗传度进行比较。

结果与结论

根据差异显著性和遗传度水平,牙齿性状分为四种类型:高、中、低和较低遗传度。第三磨牙的存在数量、牙齿大小、牙弓大小和上颌侧切牙畸形受强大的遗传影响;缺牙症显示中等遗传度;牙齿萌出和龋齿表现为低遗传度,而咬合性状的遗传度更低。这种分类便于系统了解牙齿性状的遗传特征,补充了牙齿遗传学理论。

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