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[安的列斯群岛军事人员的甲型肝炎病毒免疫状况:预防后的发病率]

[Hepatitis A virus immune status of Antilles military personnel: incidence after prophylaxis].

作者信息

Dulat C, Defrance J P, Ille H

机构信息

Laboratoire de Biologie, Direction Inter-Armées du SSA aux Antilles et en Guyane, Fort de France, Martinique.

出版信息

Med Trop (Mars). 1996;56(3):255-8.

PMID:9026592
Abstract

The purpose of this study was to ascertain the value of systematic vaccination of recruits from French overseas departments and territories (DOM-TOM) against hepatitis A. Between July 1994 and May 1995 tests to defect anti-HVA antibodies were performed on all new recruits from the French West Indies (Guadeloupe and Martinique). Of the 1685 subjects tested 346 presented type IgG anti-HVA antibodies, i.e. 20.5% overall. Seroprevalence increased from 4% in 18 year-olds to 35% in 25 year-olds and was significantly higher in recruits from Gaudeloupe (26.7%) than from Martinique (15.6%) (p < 0.001). The overall seroprevalence rate was similar to the rate observed in young recruits from mainland France in 1990. These findings indicate that hepatitis A has decreased in the French West Indies in agreement with improvements with sanitary and housing conditions. This study also supports vaccination of recruits from DOM-TOM against hepatitis A after control of their immune status.

摘要

本研究的目的是确定对来自法国海外省和海外领地(DOM-TOM)的新兵进行甲型肝炎系统疫苗接种的价值。1994年7月至1995年5月期间,对来自法属西印度群岛(瓜德罗普岛和马提尼克岛)的所有新兵进行了检测,以检测抗HVA抗体。在1685名接受检测的受试者中,有346人呈现IgG型抗HVA抗体,总体比例为20.5%。血清阳性率从18岁人群中的4%上升到25岁人群中的35%,来自瓜德罗普岛的新兵(26.7%)的血清阳性率显著高于来自马提尼克岛的新兵(15.6%)(p<0.001)。总体血清阳性率与1990年在法国本土年轻新兵中观察到的率相似。这些发现表明,随着卫生和住房条件的改善,法属西印度群岛的甲型肝炎发病率有所下降。本研究还支持在控制来自DOM-TOM的新兵的免疫状态后,对他们进行甲型肝炎疫苗接种。

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