Stam J
Afd. Neurologie, Academisch Medisch Centrum, Amsterdam.
Ned Tijdschr Geneeskd. 1996 Dec 28;140(52):2621-7.
A consensus development meeting concerning the treatment of lumbosacral radicular syndrome (LRS) by entrapment by a herniated disc or spinal stenosis was held on June 9th, 1995. It was observed that there is a lack of good evidence on many aspects of diagnosis and treatment of LRS. Agreement was reached on the thesis that the natural course of LRS is often benign. Diagnosis and treatment can usually be left to the primary care physician. Specialist consultation and ancillary investigations are only needed if an operation is indicated or in case of persistent diagnostic uncertainty. If imaging is needed MRI is preferred to CT or myelography. MRI is highly sensitive, but less specific, and may thus give false-positive results. Neurophysiologic testing may be informative in selected cases. Plain spinal X-rays are not useful in most cases. The traditional non-invasive treatments (such as bedrest, traction, physiotherapy, spinal manipulation) are not based upon convincing scientific evidence. Diagnostic imaging and invasive treatment should be considered in patients with a severe LRS that does not improve within a 4 to 8 week period. Both discectomy and chemonucleolysis are effective treatments. The principal indication is incapacitating radicular pain. There is no sound evidence that the prognosis of paresis is improved by operation. A cauda equina syndrome urgently needs surgical treatment. The efficacy of percutaneous interventions (nucleotomy, laser therapy) has not been proven. There are no strategies for the primary or secondary prevention of LRS that have demonstrated their efficacy. Psychological, social and financial factors probably contribute significantly to the occurrence of persisting symptoms after a LRS. Advice not to work after treatment for LRS may impede rehabilitation.
1995年6月9日召开了一次关于腰椎神经根综合征(LRS)由椎间盘突出或椎管狭窄导致的卡压治疗的共识发展会议。会议指出,在LRS诊断和治疗的许多方面缺乏充分的证据。会议达成共识,认为LRS的自然病程通常是良性的。诊断和治疗通常可由初级保健医生进行。只有在需要手术或诊断持续存在不确定性的情况下,才需要专科会诊和辅助检查。如果需要进行影像学检查,磁共振成像(MRI)优于计算机断层扫描(CT)或脊髓造影。MRI高度敏感,但特异性较低,因此可能会给出假阳性结果。在某些特定病例中,神经生理学检测可能会提供有用信息。在大多数情况下,普通脊柱X光片并无帮助。传统的非侵入性治疗(如卧床休息、牵引、物理治疗、脊柱推拿)并非基于令人信服的科学证据。对于严重的LRS患者,如果在4至8周内没有改善,则应考虑进行诊断性影像学检查和侵入性治疗。椎间盘切除术和化学髓核溶解术都是有效的治疗方法。主要适应症是导致功能丧失的神经根性疼痛。没有可靠证据表明手术能改善轻瘫的预后。马尾综合征急需手术治疗。经皮干预(髓核切除术、激光治疗)的疗效尚未得到证实。尚无已证明其疗效的LRS一级或二级预防策略。心理、社会和经济因素可能对LRS后持续症状的发生有重大影响。建议LRS治疗后不工作可能会阻碍康复。