Hosokawa Y, Matsuge S, Yamasaki S, Takanashi K, Satoh K, Hatakeyama H
Department of Surgery, Kinikyo-Chuo Hospital, Sapporo, Japan.
Kyobu Geka. 1997 Feb;50(2):123-7.
A total of 381 patients with primary lung cancer including 30 cases of T4 lesion, were surgically treated at our hospital from June 1975 through July 1996. Extended resection was performed in 11 patients. The 5-year survival rate after operation for all cases of T4 lung cancer, including one with operative death was 15.2%. Six patients who had curative operation showed no significant prolonged survival when compared to 24 patients who resulted in non-curative operation, but the median survival time of the former was longer than that of the latter. Six patients survived over 3 years; malignant pleurisy and/or intrathoracic dissemination of lung cancer were existed in 3 cases of those patients. In conclusion, extended resection for patients with T4 lung cancer should be limited to patients who are expected to have curative operation.
1975年6月至1996年7月,我院共对381例原发性肺癌患者进行了手术治疗,其中包括30例T4期病变患者。11例患者接受了扩大切除术。包括1例手术死亡患者在内的所有T4期肺癌患者术后5年生存率为15.2%。6例接受根治性手术的患者与24例接受非根治性手术的患者相比,生存时间无显著延长,但前者的中位生存时间长于后者。6例患者存活超过3年;其中3例患者存在恶性胸膜炎和/或肺癌胸腔内播散。总之,T4期肺癌患者的扩大切除术应仅限于预期能进行根治性手术的患者。