Kendler K S
Virginia Commonwealth University/MCV, Richmond 23298-0126, USA.
Soc Psychiatry Psychiatr Epidemiol. 1997 Jan;32(1):5-11. doi: 10.1007/BF00800661.
Psychiatric genetic epidemiology has, as a field, undergone considerable change in the last two decades. My goal here is to provide a brief, selective and inevitably personal overview of where the field has come from, where it is now and where it might be going. Methodologic issues will be emphasized, particularly those of an "epidemiologic" nature. I will organize this review around three of the major methods used in psychiatric genetics: family studies, twin studies and linkage studies.
在过去二十年里，精神科遗传流行病学作为一个领域经历了相当大的变革。我在此的目标是对该领域的起源、现状及未来走向提供一个简要、有所侧重且不可避免地带有个人观点的概述。将重点强调方法学问题，尤其是那些具有“流行病学”性质的问题。我将围绕精神遗传学中使用的三种主要方法来组织这篇综述：家系研究、双生子研究和连锁研究。
