Maekawa S, Kumanogoh H, Funatsu N, Takei N, Inoue K, Endo Y, Hamada K, Sokawa Y
Department of Biotechnology, Faculty of Textile Science, Kyoto Institute of Technology, Japan.
Biochim Biophys Acta. 1997 Jan 14;1323(1):1-5. doi: 10.1016/s0005-2736(96)00222-2.
NAP-22 is a membrane-localized brain enriched acidic protein having a Ca(2+)-dependent calmodulin binding activity. Further fractionation of the NAP-22 containing membrane showed the localization of NAP-22 in a Triton insoluble fraction of low density. Besides NAP-22, this fraction was found to contain GAP-43 (neuromodulin), trimeric G proteins, and some GPI-anchored proteins such as Thy-1 and N-CAM-120. Presence of some protein tyrosine kinases, such as src and fyn, was also shown.
