Biederman J, Faraone S V, Marrs A, Moore P, Garcia J, Ablon S, Mick E, Gershon J, Kearns M E
Joint Program in Pediatric Psychopharmacology, Massachusetts General Hospital, Boston, MA 02114, USA.
J Am Acad Child Adolesc Psychiatry. 1997 Feb;36(2):214-23. doi: 10.1097/00004583-199702000-00012.
This report examines the clinical features and correlates of juvenile panic disorder in referred children and adolescents to test specific hypotheses about its relationship with adult panic disorder.
The sample consisted of consecutively referred children and adolescents (N = 472) comprehensively evaluated with structured diagnostic interviews, cognitive tests, and psychosocial assessments.
Panic disorder was identified in 6% and agoraphobia in 15% of psychiatrically referred children and adolescents. Children meeting criteria for panic disorder also frequently met criteria for agoraphobia. The latter disorder was more prevalent and had an earlier age at onset than panic disorder. Children with panic disorder and those with agoraphobia had similar correlates with frequent comorbidity with other anxiety and mood disorders. A high level of comorbidity with disruptive disorders was also identified.
These results support the hypothesis of continuity between the juvenile and the adult form of panic disorder. However, the high level of comorbidity with disruptive behavior disorders also suggests developmentally specific discontinuities between juveniles and adults with panic disorder.
本报告研究了转诊儿童和青少年中青少年惊恐障碍的临床特征及其相关因素,以检验关于其与成人惊恐障碍关系的特定假设。
样本包括连续转诊的儿童和青少年(N = 472),通过结构化诊断访谈、认知测试和心理社会评估进行全面评估。
在接受精神科转诊的儿童和青少年中,6%被诊断为惊恐障碍,15%被诊断为广场恐惧症。符合惊恐障碍标准的儿童也经常符合广场恐惧症的标准。后一种障碍比惊恐障碍更普遍,发病年龄更早。患有惊恐障碍的儿童和患有广场恐惧症的儿童与其他焦虑和情绪障碍频繁共病的相关因素相似。还发现与破坏性行为障碍的共病率很高。
这些结果支持青少年和成人形式的惊恐障碍之间存在连续性的假设。然而,与破坏性行为障碍的高共病率也表明,患有惊恐障碍的青少年和成人之间存在发育上的特定不连续性。