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Progress in an oral vaccine for amebiasis. Expression of the serine rich Entamoeba histolytica protein (SREHP) in the avirulent vaccine strain Salmonella typhi TY2 chi 4297 (delta cya delta crp delta asd): safety and immunogenicity in mice.

作者信息

Zhang T, Stanley S L

机构信息

Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.

出版信息

Arch Med Res. 1997;28 Spec No:269-71.

PMID:9033097
Abstract
摘要

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1
Progress in an oral vaccine for amebiasis. Expression of the serine rich Entamoeba histolytica protein (SREHP) in the avirulent vaccine strain Salmonella typhi TY2 chi 4297 (delta cya delta crp delta asd): safety and immunogenicity in mice.
Arch Med Res. 1997;28 Spec No:269-71.
2
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Oral immunization with the dodecapeptide repeat of the serine-rich Entamoeba histolytica protein (SREHP) fused to the cholera toxin B subunit induces a mucosal and systemic anti-SREHP antibody response.用与霍乱毒素B亚基融合的富含丝氨酸的溶组织内阿米巴蛋白（SREHP）的十二肽重复序列进行口服免疫，可诱导黏膜和全身抗SREHP抗体反应。
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