Vile R G
Imperial Cancer Research Fund Laboratory of Cancer Gene Therapy, St. Thomas' Hospital, London, UK.
Cancer Metastasis Rev. 1996 Sep;15(3):403-10. doi: 10.1007/BF00046350.
Previous chapters have shown that there are a large number of therapeutic approaches under consideration for the gene therapy of cancer. Many of these have progressed into Phase I clinical trials. However, many of the early results are perceived to be disappointing in terms of low levels of gene transfer and systemic efficacy. In this concluding chapter, possible solutions to this state of unease are addressed, so that gene therapy of cancer can resume on its course to become a major contributor to clinical oncology in the years ahead.
前面的章节已经表明，在癌症基因治疗方面有大量治疗方法正在研究中。其中许多已经进入了I期临床试验。然而，许多早期结果在基因转移水平和全身疗效方面被认为令人失望。在这最后一章中，针对这种令人不安的状况提出了可能的解决方案，以便癌症基因治疗能够继续前行，在未来几年成为临床肿瘤学的主要贡献力量。
