Falcini F, Taccetti G, Ermini M, Trapani S, Matucci Cerinic M
Department of Pediatrics-Rheumatology Unit, Meyer Hospital, University of Florence, Italy.
J Rheumatol. 1997 Feb;24(2):389-92.
Catastrophic antiphospholipid antibody syndrome, reported in a minority of patients with circulating antiphospholipid antibodies, is characterized by widespread vascular occlusions. The term "catastrophic" has been used to describe the severity of symptomatology, sometimes leading to death. We describe a girl aged 11 years, fulfilling diagnostic criteria for systemic lupus erythematosus, with recurrent episodes of thromboembolic phenomena involving lung and skin, complicated with disseminated intravascular coagulation. Treatment with warfarin ultimately resulted in effective control of the disease.
灾难性抗磷脂抗体综合征在少数循环抗磷脂抗体阳性患者中被报道，其特征为广泛的血管闭塞。“灾难性”一词用于描述症状的严重程度，有时会导致死亡。我们描述了一名11岁女孩，符合系统性红斑狼疮的诊断标准，反复出现累及肺部和皮肤的血栓栓塞现象，并并发弥散性血管内凝血。华法林治疗最终有效控制了该疾病。
