大鼠味觉厌恶学习中远程和近端超声预暴露及衰老效应

Remote and proximal US preexposure and aging effects in taste aversion learning in rats.

作者信息

Misanin J R, Hoefel T D, Riedy C A, Hinderliter C F

机构信息

Department of Psychology, Susquehanna University, Selinsgrove, PA 17870-1001, USA.

出版信息

Physiol Behav. 1997 Feb;61(2):221-4. doi: 10.1016/s0031-9384(96)00371-x.

DOI:10.1016/s0031-9384(96)00371-x

PMID:9035251

Abstract

Age as a factor in the effect of proximal and remote unconditioned stimulus (US) preexposure on conditioned taste aversion in weanling, young adult, and old rats was studied in 2 experiments. In Experiment 1, 6 daily US preconditioning exposures attenuated conditioning in weanlings and young adults, but not in old rats. In Experiment 2, exposure to a single US 1 h before the conditioning trial curtailed conditioning at all age levels. These results are explained in terms of age differences in familiarity with the conditioning context and Wagner's information-processing model for self- and retrieval-generated disruption of conditioning.

摘要

在两项实验中，研究了年龄作为近端和远端无条件刺激（US）预暴露对断奶期、成年期和老年大鼠条件性味觉厌恶影响的一个因素。在实验1中，每天进行6次US预条件暴露会减弱断奶期和成年期大鼠的条件反射，但对老年大鼠没有影响。在实验2中，在条件性试验前1小时暴露于单个US会在所有年龄组中减少条件作用。这些结果根据对条件作用情境的熟悉程度的年龄差异以及瓦格纳关于自我和检索产生的条件作用破坏的信息处理模型来解释。