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大鼠长期延迟味觉厌恶条件反射中情境 - 疾病关联不存在年龄差异。

Lack of age differences in context-illness associations in the long-delay taste-aversion conditioning of rats.

作者信息

Misanin J R, Hinderliter C F

机构信息

Department of Psychology, Susquehanna University, Selinsgrove, PA 17870, USA.

出版信息

Percept Mot Skills. 1995 Apr;80(2):595-8. doi: 10.2466/pms.1995.80.2.595.

Abstract

To evaluate whether previously observed age differences in long-delay taste aversion were due to age-related differences in the shared association of contextual cues and CS with the US, weanling, young-adult, and old-adult rats were given a NaCl or LiCl US immediately after or a LiCl US 3 hr. after a saccharin CS presentation in a black or white context. They were then given a context-preference test in a chamber which was half black and half white. Analysis showed rats, irrespective of age or conditioning context, spent a significantly smaller percentage of time on the white side than on the black side of the test chamber. These results suggest that age differences in long-delay taste-aversion conditioning are not due to age-related differences in the shared association of contextual cues and CS with the US.

摘要

为了评估之前观察到的长延迟味觉厌恶中的年龄差异是否是由于情境线索和条件刺激与非条件刺激的共同关联中与年龄相关的差异所致,将断奶期、年轻成年期和老年成年期的大鼠在糖精条件刺激在黑色或白色情境中呈现后立即给予氯化钠或氯化锂非条件刺激,或者在糖精条件刺激呈现3小时后给予氯化锂非条件刺激。然后在一个一半是黑色一半是白色的实验箱中对它们进行情境偏好测试。分析表明,无论年龄或条件作用情境如何,大鼠在测试箱白色一侧停留的时间百分比显著低于黑色一侧。这些结果表明,长延迟味觉厌恶条件作用中的年龄差异并非由于情境线索和条件刺激与非条件刺激的共同关联中与年龄相关的差异所致。

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