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[梦-睡眠-觉醒周期的机制]

[Mechanisms of dream-sleep-wakefulness cycle].

作者信息

Valatx J L

机构信息

INSERM U52, Université Claude-Bernard, Lyon.

出版信息

Rev Prat. 1996 Dec 15;46(20):2404-10.

PMID:9035524
Abstract

For the occurrence of each state of sleep (slow wave sleep, paradoxical sleep) there are two neuronal networks. The first one called executive is responsible for the sleep phenomenology; the second called permissive is for the triggering of sleep. Wakefulness depends on a very complex system (10 structures) including the permissive networks which inhibit sleep. Sleep onset is thought as a blockade of the waking state by an antiwake network synthesizing hypnogenic factors. Such a regulation allows to suggest that insomnia is a wake trouble depending on a revisited therapy.

摘要

对于睡眠的每种状态(慢波睡眠、异相睡眠)的出现,存在两个神经元网络。第一个称为执行网络,负责睡眠现象学;第二个称为许可网络,用于触发睡眠。觉醒依赖于一个非常复杂的系统(10个结构),包括抑制睡眠的许可网络。睡眠开始被认为是由合成催眠因子的抗觉醒网络对清醒状态的阻断。这种调节表明,失眠是一种依赖于重新审视的治疗方法的觉醒障碍。

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