Ostertag P, Leunig A, Grevers G
Klinik und Poliklinik für Hals-, Nasen- und Ohrenkranke der Ludwig-Maximilians Universität, München.
Laryngorhinootologie. 1996 Oct;75(10):619-22. doi: 10.1055/s-2007-997645.
The central giant-cell (reprative) granuloma is an uncommon bone lesion usually located in the mandible and maxilla. In contrast to giant cell tumors of the extra-craniofacial skeleton, the origin of this lesion is considered to be non-neoplastic, reactive, and triggered by trauma or inflammation. The tumor occurs mainly in young people; they complain of regional indolent swelling of the jaw eventually leading to loosening of the teeth.
In the paper, the authors describe the unusual case of a central giant-cell granuloma in a young male. Diagnostic procedures, adequate therapeutic approach, and an overview of differential diagnostic considerations are provided.
The pedunculate tumor was removed surgically. In endoscopic controls no recurrent growth has been seen up to one year after removal.
Even though the giant-cell reparative granuloma is rare, it may also occur in the nasal cavity. Diagnosis is established by histologic findings and the typical clinical appearance. Surgical removal is the treatment of choice.
中央巨细胞（修复性）肉芽肿是一种罕见的骨病变，通常位于下颌骨和上颌骨。与颅外面骨骼的巨细胞瘤不同，这种病变的起源被认为是非肿瘤性、反应性的，由创伤或炎症引发。该肿瘤主要发生在年轻人中；他们主诉颌部出现无痛性局部肿胀，最终导致牙齿松动。
在本文中，作者描述了一名年轻男性发生中央巨细胞肉芽肿的罕见病例。文中提供了诊断程序、适当的治疗方法以及鉴别诊断考虑因素的概述。
带蒂肿瘤通过手术切除。在内镜检查中，切除后长达一年未见复发生长。
尽管巨细胞修复性肉芽肿罕见，但也可能发生在鼻腔。通过组织学检查结果和典型的临床表现进行诊断。手术切除是首选治疗方法。
